Customer Publication
Comparison of Real-Time Methods Demonstrating the Effects of Reduced Glutathione on Olfactory Neuroblasts
Journal: Applied Sciences (2025)
Research Areas: Cell research
Cell Lines: 13s24 (lfactory neuroblast cell line)
Summary: Researchers explored how a common antioxidant, reduced glutathione (GSH), affects brain-derived cells. They found that GSH makes these cells swell, move more, and stick less to their surroundings. Within just six hours, GSH disrupted the cell’s internal scaffolding and surface molecules, weakening their grip. This suggests that GSH can influence proteins controlling how nerve cells grow, divide, and migrate—processes essential for brain development and plasticity. The study also shows why real-time, label-free methods are so valuable: they capture these rapid changes while avoiding the limitations of slower, more complex techniques. HoloMonitor M4 was used to study the cell morphology and cell motility.