June 27, 2017

Live Cell Imaging Made Easy

Phase Holographic Imaging provides an innovative tool that lets you contin­u­ously image and monitor your cells directly inside your incubator.

Our HoloMonitor® M4 is a small micro­scope designed to operate 24/7, inside your normal incubator. Without any labels or stains, it uses digital holography to record your cells in real-time.

The result is real 3D images and quanti­tative data on your cultures, all the way down to single-cell level, collected in a completely non-invasive way.

Get ahead with tomorrow's live cell imaging today!

Key benefits with the HoloMonitor system

HoloMonitor M4 is designed to operate 24/7, directly inside your normal incubator. This gives you the possibility to continuously record your cells in their natural environment, making sure you don't miss any important cellular events in your culture.
HoloMonitor M4 is based on digital holography, meaning that the cells in your culture are imaged with nothing but light. The technique doesn't require any additives to the cell culture medium, nor does it require antibodies or stains to visualize your cells. The images are built from the low-energy light beam, alone.
The HoloMonitor App Suite software will reconstruct your cells in 3D, immediately providing you with quantitative information about each cell. More than 30 different morphological parameters are calculated automatically, such as cell area, thickness and volume. Of course, all data can be compiled, exported and analyzed at population level as well.
The HoloMonitor App Suite software offers a wide range of applications, each designed to allow for easy setup and analysis of a specific kind of experiment. We offer both end-point oriented applications, such as an automatic cell counter, and kinetic applications, such as cell tracking and dose-response assays.

HoloMonitor and the App Suite software is developed with user-friendliness in mind. Just place your cell culture vessel onto the microscope and let the intuitive software guide you through the experimental setup. When finished, relevant results are generated automatically. Naturally, you can export all underlying data to make your own analysis as well.

The HoloMonitor system allows for quick and guided experimental setup, runs the imaging completely automatic, and doesn't require any reagents to run. Furthermore, you can reanalyze one experiment in multiple ways, generating several results from fewer cells. Taken together, these aspects save you time, money and cells.

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The latest from PHI

New publication out in Biology Open! Norwegian scientists have developed two protocols for quality controlling the ploidy of HAP1 cells. HoloMonitor® M4 was used to study cell morphology, growth kinetics and motility.

PHI highlights

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Live cell analysis in the incubator

Do you wonder how live cell imaging with HoloMonitor® fits your research needs?

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We can image live cells from our lab for you or show the ease of data analysis with our wide application portfolio.

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