Reduced glutathione decreases cell adhesion and increases cell volume
Research Areas: Cell research
Utility of Novel Drug Targets for Treatment of Metastatic Cancer
Research Areas: Cancer Research
PIP5K1α is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer
Research Areas: Cancer research
Self-Organization of Tissue Growth by Interfacial Mechanical Interactions in Multilayered Systems
Research Areas: Cell study
Chlorine exposure induces Caspase-3 independent cell death in human lung epithelial cells
Research Areas: Toxicology
Interfering with pak4 Protein Expression Affects Osteosarcoma Cell Proliferation and Migration
Research Areas: Cancer research
BRAFV600E induces reversible mitotic arrest in human melanocytes via microRNA-mediated suppression of AURKB
Research Areas: Cancer research
Digital holographic microscopy: a noninvasive method to analyze the formation of spheroids
Research Areas: Cancer research
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis
Research Areas: Cancer Research
Mast cell tryptase enhances wound healing by promoting migration in human bronchial epithelial cells
Research Areas: Cell research
Breast cancer cell line toxicity of a flavonoid isolated from Baccharis densiflora
Research Areas: Cancer research
Effect of three-dimensional ECM stiffness on cancer cell migration through regulating cell volume homeostasis
Research Areas: Cancer research
IL4 promotes phagocytosis of murine leukemia cells counteracted by CD47 upregulation
Research Areas: Leukemia
Externally added cystatin C reduces growth of A375 melanoma cells by increasing cell cycle time
Research Areas: Cancer research
Evaluation of the Toxicity on Lung Cells of By-Products Present in Naphthalene Secondary Organic Aerosols
Research Areas: Aerosol toxicity
Epac1 signaling pathway mediates the damage and apoptosis of inner ear hair cells after noise exposure in a rat model
Research Areas: Hearing loss studies
Monobutyl phthalate can induce autophagy and metabolic disorders by activating the ire1a-xbp1 pathway in zebrafish liver
Research Areas: Chemical toxicity
Monoclonal antibody 2C5 specifically targets neutrophil extracellular traps
Research Areas: Cell Research
Targeted inhibition of ERα signaling and PIP5K1α/Akt pathways in castration‐resistant prostate cancer
Research Areas: Cancer research
Efficient and crucial quality control of HAP1 cell ploidy status
Research Areas: Cell Research
Smart drug combinations for cervical cancer: dual targeting of Bcl-2 family of proteins and aurora kinases
Research Areas: Cancer research
Exploiting the potential of commercial digital holographic microscopy by combining it with 3D matrix cell culture assays
Research Areas: Method Development
SUMOylation of PUM2 promotes the vasculogenic mimicry of glioma cells via regulating CEBPD
Research Areas: Cancer research
Improved Autophagic Flux in Escapers from Doxorubicin-Induced Senescence/Polyploidy of Breast Cancer Cells
Research Areas: Cancer research
Monobutyl phthalate (MBP) induces energy metabolism disturbances in the gills of adult zebrafish (Danio rerio)
Research Areas: Chemical toxicity
Subpopulations of Organoid-Forming Cells Have Different Motility
Research Areas: Organoid formation
The osteogenic commitment of CD271+CD56+ bone marrow stromal cells (BMSCs) in osteoarthritic femoral head bone
Research Areas: Stem cell therapy
Label-Free Classification of Apoptosis, Ferroptosis and Necroptosis Using Digital Holographic Cytometry
Research Areas: Basic Cell Research
Assembly of Epithelial Monolayers and Transmigration of Cancer Cells Captured with Phase Holographic Imaging
Research Areas: Cancer research
MicroRNA-362-3p Inhibits Migration and Invasion via Targeting BCAP31 in Cervical Cancer
Research Areas: Cancer research
Defining COMMD4 as an anti-cancer therapeutic target and prognostic factor in non-small cell lung cancer
Research Areas: Cancer research
Exosomes derived from mesenchymal stem cells repair a Parkinson’s disease model by inducing autophagy
Research Areas: Stem cell therapy
The human papillomavirus confers radiosensitivity in oropharyngeal cancer cells by enhancing DNA double strand break
Research Areas: Cancer research
Alkyl-carbon chain length of two distinct compounds and derivatives are key determinants of their anti-Acanthamoeba activities
Research Areas: Parasitic infections
N-terminal acetylation of actin by NAA80 is essential for structural integrity of the golgi apparatus
Research Areas: Cell Research
Antibacterial AZT derivative regulates metastasis of breast cancer cells
Research Areas: Cancer research
BCAP31, a cancer/testis antigen-like protein, can act as a probe for non-small-cell lung cancer metastasis
Research Areas: Cancer research
Berberine Maintains the Neutrophil N1 Phenotype to Reverse Cancer Cell Resistance to Doxorubicin
Research Areas: Frontiers in Pharmacology
LRIG1 in lung cancer: prognostic effects and mechanistic studies
Research Areas: Cancer Research
Development of label-free biophysical markers in osteogenic maturation
Research Areas: Cell Research
KLF2+ stemness maintains human mesenchymal stem cells in bone regeneration
Research Areas: Stem cell therapy
Synthesis of a dihalogenated pyridinyl silicon rhodamine for mitochondrial imaging by a halogen dance rearrangement
Research Areas: Flourofore synthesis
Propofol prevents oxidative stress and apoptosis by regulating iron homeostasis and targeting JAK/STAT3 signaling in SH-SY5Y cells
Research Areas: Neurodegenerative disorders
Unravelling the role of trophoblastic-derived extracellular vesicles in in regulatory T cell differentiation
Research Areas: Cell Research
Exploring the Natural Piericidins as Anti-Renal Cell Carcinoma Agents Targeting Peroxiredoxin 1
Research Areas: Cytotoxicity
The long noncoding RNA TP73‐AS1 promotes tumorigenicity of medulloblastoma cells
Research Areas: Cancer research
ITGA2 as a potential nanotherapeutic target for glioblastoma
Research Areas: Cancer research
In vitro SOD-like activity of mono- and di-copper complexes with a phosphonate substituted SALAN-type ligand
Research Areas: Cytotoxicity
Effects of GADL1 overexpression on cell migration and the associated morphological changes
Research Areas: Bipolar disorder treatment
Whole-Cell Multiparameter Assay for Ricin and Abrin Activity-Based Digital Holographic Microscopy
Research Areas: Cytotoxicity
Digital Holographic Cytometry: Macrophage Uptake of Nanoprobes
Research Areas: Cytotoxicity
Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis
Research Areas: Cancer research
Preparation of fibrin hydrogels to promote the recruitment of anti-inflammatory macrophages
Research Areas: Tissue regeneration
Metabolism of diethyl phthalate (DEP) and identification of degradation intermediates by Pseudomonas sp. DNE-S1
Research Areas: Biodegradation
Hippo pathway controls cell adhesion and context-dependent cell competition to influence skin engrafment efficiency
Research Areas: Skin engraftment
The photocytotoxicity effect of cationic sulfonated corrole towards lung cancer cells: in vitro and in vivo study
Research Areas: Cancer research
Moving into a New Dimension: Tracking Migrating Cells with Digital Holographic Cytometry in 3D
Research Areas: Cancer research
Nuclear respiratory factor 1 acting as an oncoprotein drives estrogen-induced breast carcinogenesis
Research Areas: Cancer research
Lack of LTβR Increases Susceptibility of IPEC-J2 Cells to Porcine Epidemic Diarrhea Virus
Research Areas: Cell research
The connection between the cardiac glycoside‐induced senescent cell morphology and Rho/Rho kinase pathway
Research Areas: Cancer research
Evaluation of Holographic Imaging Cytometer HoloMonitor M4 Motility Applications
Research Areas: Cancer research
Single cell analysis of proliferation and movement of cancer and normal-like cells on nanowire array substrates
Research Areas: Nanomaterials and cell interactions
Ulleungdin, a lasso peptide with cancer cell migration inhibitory activity discovered by the genome mining approach
Research Areas: Cancer Research
TRPM2 Modulates Neutrophil Attraction to Murine Tumor Cells by Regulating CXCL2 Expression
Research Areas: Immunoncology
Hexagonal Boron Nitride Functionalized with Au Nanoparticles—Properties and Potential Biological Applications
Research Areas: Biocompatibility
General Cytotoxicity and Its Application in Nanomaterial Analysis
Research Areas: Nanomateiral
Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation
Research Areas: Melanoma
Quantitative Phase Imaging for Label-Free Analysis of Cancer Cells—Focus on Digital Holographic Microscopy
Research Areas: Digital holography technology
Quantitative evaluation of morphological changes in activated platelets in vitro using digital holographic microscopy
Research Areas: Platelet activation
The impact of circulating preeclampsia-associated extracellular vesicles on the migratory activity and phenotype of THP-1 monocytic cells
Research Areas: Pathogenesis in preeclampsia
The evolution of phase holographic imaging from a research idea to publicly traded company
Research Areas: Quantitative phase microscopy
Quantification of mammalian tumor cell state plasticity with digital holographic cytometry
Research Areas: Melanoma
Applications of quantitative time lapse holographic imaging to the development of complex pharmaceutical nano formulations
Research Areas: Method development
A Time-lapse, Label-free, Quantitative Phase Imaging Study of Dormant and Active Human Cancer Cells
Research Areas: Cancer Research
β-Nitrostyrene 1 derivatives attenuate LPS-mediated acute lung injury via the 2 inhibition of neutrophil-platelet interactions and NET release
Research Areas: Acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS)
Tau Phosphorylation and Amyloid-β Deposition in the Presence of Formaldehyde
Research Areas: Alzheimer’s disease
NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression
Research Areas: Cancer research
The role of Vimentin in Regulating Cell Invasive Migration in Dense Cultures of Breast Carcinoma Cells
Research Areas: Cancer research
A Biophysical Approach to Quantify Skeletal Stem Cells Trans-differentiation as a Model for the Study of Osteoporosis
Research Areas: Stem cell research
Interleukin-6 blockade attenuates lung cancer tissue construction integrated by cancer stem cells
Research Areas: Cancer research
CFTR supports cell death through ROS-dependent activation of TMEM16F (anoctamin 6)
Research Areas: Cystic fibrosis
Synthesis, Characterization and in Vitro and in Vivo Photodynamic Activities of a Gallium(III) Tris(Ethoxycarbonyl)corrole
Research Areas: Photo-cytotoxicity; photodynamic therapy (PDT)
Hypoxia-inducible Factor-1 Alpha Is Involved in Rip-induced Necroptosis Caused by in Vitro and in Vivo Ischemic Brain Injury
Research Areas: Ischemic brain injury
Hydroxylated Fluorescent Dyes for Live-cell Labeling: Synthesis, Spectra and Super-resolution Sted
Research Areas: Method development
Label-free High Temporal Resolution Assessment of Cell Proliferation Using Digital Holographic Microscopy
Research Areas: Digital holography technology
Characterization of a Transgenic Mouse Model Exhibiting Spontaneous Lung Adenocarcinomas With a Metastatic Phenotype
Research Areas: Cancer research
The “inherent Vice” in the Anti-angiogenic Theory May Cause the Highly Metastatic Cancer to Spread More Aggressively
Research Areas: Cancer research
Promising Anticancer Activity of Cyclotrichium Niveum L. Extracts Through Induction of Both Apoptosis and Necrosis
Research Areas: Cancer research
Characterization of Dormant and Active Human Cancer Cells by Quantitative Phase Imaging
Research Areas: Angiogenesis
Holography: the Usefulness of Digital Holographic Microscopy for Clinical Diagnostics
Research Areas: Holography technology
Loss of Erα Induces Amoeboid-like Migration of Breast Cancer Cells by Downregulating Vinculin
Research Areas: Cancer research
Three-dimensional Morphology of C6/36 Cells Infected by Dengue Virus: a Study Based on Digital Holographic Microscopy
Research Areas: Virus infection
Supervised Classification of Etoposide-treated in Vitro Adherent Cells Based on Noninvasive Imaging Morphology
Research Areas: Image-based analysis, cell classification
Cathelicidins Positively Regulate Pancreatic Β-cell Functions
Research Areas: Immunregulation
Ca2+ signals, cell membrane disintegration, and activation of tmem16f during necroptosis
Research Areas: Cell death
Relationship Between tmem16a/anoctamin 1 and lrrc8a
Research Areas: Basic cell research
Shielding of the Geomagnetic Field Alters Actin Assembly and Inhibits Cell Motility in Human Neuroblastoma Cells
Research Areas: Mode of action
Enhanced Cytotoxicity of Folic Acid-targeted Liposomes Co-loaded With C6 Ceramide and Doxorubicin: in Vitro Evaluation on HeLa, A2780-ADR and H69-AR Cells
Research Areas: Cancer research, Drug development
See in 3D: state of the art of 3D display technologies
Research Areas: Digital holography technology
Macrophage Polarization and the Effect of Microrna-155 Administered in Water-in-oil-in-water Multiple Emulsion Formulations
Research Areas: Cancer research, immunology
Interfacing Antibody-based Microarrays and Digital Holography Enables Label-free Detection for Loss of Cell Volume
Research Areas: Cancer research, drug development
Induction of Morphological Changes in Death-induced Cancer Cells Monitored by Holographic Microscopy
Research Areas: Cell research
Environmental and Toxicological Impacts of Glyphosate With Its Formulating Adjuvant
Research Areas: Drug development
Nanowires in Cell Biology – Exploring Interactions and Applications
Research Areas: Nanowires
Digital Holographic Microscopy for Non-invasive Monitoring of Cell Cycle Arrest in L929 Cells
Research Areas: Method development
Edaravone Protects Against Methylglyoxal-induced Barrier Damage in Human Brain Endothelial Cells
Research Areas: Drug development
Protein kinase A (PKA) pathway is functionally linked to androgen receptor (AR) in the progression of prostate cancer
Research Areas: Cancer research
Fibroblasts Cultured on Nanowires Exhibit Low Motility, Impaired Cell Division, and Dna Damage
Research Areas: Nanomaterials
Cells and Holograms — Holograms and Digital Holographic Microscopy as a Tool to Study the Morphology of Living Cells
Research Areas: Digital holographic technology
A Unifying Mechanism for Cancer Cell Death Through Ion Channel Activation by Hamlet
Research Areas: Action of HAMLET
Prevention and Treatment of Colon Cancer by Peroral Administration of Hamlet
Research Areas: Action of HAMLET
Low Resolution Solution Structure of Hamlet and the Importance of Its Alpha-domains in Tumoricidal Activity
Research Areas: Action of HAMLET
HAMLET: Functional Properties and Therapeutic Potential
Research Areas: Action of HAMLET
Dermatan Sulfate Is Involved in the Tumorigenic Properties of Esophagus Squamos Cell Carcinom
Research Areas: Cancer research
HAMLET Binding to Α-actinin Facilitates Tumor Cell Detachment
Research Areas: Action of HAMLET
Generation of Trisomies in Cancer Cells by Multipolar Mitosis and Incomplete Cytokinesis
Research Areas: Cancer research
Digital Holographic Microscopy — Innovative and Non-destructive Analysis of Living Cells
Research Areas: Digital holographic technology
Cell motility studies using digital holographic microscopy
Research Areas: Digital holographic technology
Non-invasive, Label-free Cell Counting and Quantitative Analysis of Adherent Cells Using Digital Holography
Research Areas: Digital holographic technology
Design of Reconfigurable Hardware Architectures for Real-Time Applications
Research Areas: Digital holography technology
A Hardware Acceleration Platform for Digital Holographic Imaging
Research Areas: Digital holographic technology
Modeling and Exploration of a Reconfigurable Architecture for Digital Holographic Imaging
Research Areas: Background technology
Object Characterization With Refractometric Digital Fourier Holography
Research Areas: Digital holographic technology
High-resolution Digital Transmission Microscopy — a Fourier Holography Approach
Research Areas: Digital holographic technology
Refractometry of Microscopic Objects With Digital Holography
Research Areas: Digital holography technology
Customer Publications
Below you will find summaries and links to peer-reviewed publications and book chapters discussing HoloMonitor, its applications and the core technology — digital holographic and quantitative phase imaging (QPI) microscopy.
Featured Publications
Exploiting the potential of commercial digital holographic microscopy by combining it with 3D matrix cell culture assays
Research Areas: Method Development
Cell Lines: NCL-H524, U2OS
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Digital Holographic Imaging as a Method for Quantitative, Live Cell Imaging of Drug Response to Novel Targeted Cancer Therapies
Research Areas: Cancer research
Cell Lines: HeLa
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Evaluation of Holographic Imaging Cytometer HoloMonitor M4 Motility Applications
Research Areas: Cancer research
Cell Lines: 1205Lu and WM793
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Reduced glutathione decreases cell adhesion and increases cell volume
Research Areas: Cell research
Cell Lines: A549
Utility of Novel Drug Targets for Treatment of Metastatic Cancer
Research Areas: Cancer Research
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PIP5K1α is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer
Research Areas: Cancer research
Cell Lines: LNCaP C4-2, DU145
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A New Class of PSMA-617-Based Hybrid Molecules for Preoperative Imaging and Intraoperative Fluorescence Navigation of Prostate Cancer
Research Areas: Oncology
Cell Lines: LNCaP, PC-3
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Self-Organization of Tissue Growth by Interfacial Mechanical Interactions in Multilayered Systems
Research Areas: Cell study
Cell Lines: HeLa, HepG2, MDCK, MDA-MB-231, U2OS, B16F10, and MEFs
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Pigment Epithelium Derived Factor Is Involved in the Late Phase of Osteosarcoma Metastasis by Increasing Extravasation and Cell-Cell Adhesion
Research Areas: Cancer Research
Cell Lines: 143B, TKD2 cell
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Chlorine exposure induces Caspase-3 independent cell death in human lung epithelial cells
Research Areas: Toxicology
Cell Lines: A549
Label-Free Study of the Global Cell Behavior during Exposure to Environmental Radiofrequency Fields in the Presence or Absence of Pro-Apoptotic or Pro-Autophagic Treatments
Cell Lines: SH-SY5Y, HCT116, primary neuronal cells from Sprague–Dawley rat, rat primary cortical astrocytes
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Interfering with pak4 Protein Expression Affects Osteosarcoma Cell Proliferation and Migration
Research Areas: Cancer research
Cell Lines: U2-OS, MG-63 and hFOB
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Essential Oils from Zingiber striolatum Diels Attenuate Inflammatory Response and Oxidative Stress through Regulation of MAPK and NF-κB Signaling Pathways
Research Areas: Inflammation
Cell Lines: RAW 264.7
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BRAFV600E induces reversible mitotic arrest in human melanocytes via microRNA-mediated suppression of AURKB
Research Areas: Cancer research
Cell Lines: Benign human melanocytic nevi, 501Mel, HCIMel019
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Digital holographic microscopy: a noninvasive method to analyze the formation of spheroids
Research Areas: Cancer research
Cell Lines: HT29
