Without requiring labels, the HoloMonitor® Cell Motility Assay allows cell-friendly and fully automated cell motility and migration studies, directly in your incubator.
Study unlabeled cells in the cell incubator, as long as needed, to get relevant motility and migration data. This enables both kinetic cell motility studies providing cell population data and tracking of single cells, using the Single-cell Tracking software.
The HoloMonitor® Cell Motility Assay is designed to explore the average motility of cells in a population and is ideal for studies investigating how various treatments, drug candidates, or environments, influence cell movement over time. Analyze long-term cellular movement when using your standard cell growth media and environment — without labeling, staining or phototoxicity.
The HoloMonitor App Suite software automatically analyzes and presents motility data in terms of speed kinetics, i.e. average cell speed over time, and accumulated mean distance, at each time point. Note that the result presentation is immediate and progresses as the experiment proceeds.
Yuntian Zhang and Robert L. Judson, Evaluation of holographic imaging cytometer holomonitor M4® motility applications, Cytometry Part A (2018)
Francesco Casciello et al., G9a-mediated repression of CDH10 in hypoxia enhances breast tumour cell motility and associates with poor survival outcome, Theranostics (2020)
The software automatically presents cell motility data for the cell populations. If preferred, all data can easily be exported to Excel for further analysis.
Experiments set up using App Suite software can easily be re-analyzed to generate results for another assay type. For example, for a motility experiment, proliferation results can be achieved from the same experimental data.
After imaging the undestroyed cells, or the supernatant, can be used again for additional analysis using other methods.
Motility and migration studies of single cells, or sub-populations of cells, can be performed using the Single-cell Tracking software.
HoloMonitor provides methodology for label-free imaging of living cells. We use HoloMonitor for studying the effect of drugs on cell morphology, viability, death and motility of cancer cells.
Faculty of Health and Society, Malmö University
Do you wonder how live cell imaging with HoloMonitor® fits your research needs?
We can image live cells from our lab for you or show the ease of data analysis with our wide application portfolio.
Our product experts and application specialists are happy to answer your questions.