Cell Motility Assay

Differ cell motility from cell migration

Without requiring labels, the HoloMonitor® Cell Motility Assay allows cell-friendly and fully automated cell motility and migration studies, directly in your incubator.

Study unlabeled cells in the cell incubator, as long as needed, to get relevant motility and migration data. This enables both kinetic cell motility studies providing cell population data and tracking of single cells, using the Single-cell Tracking software.

Explore how cell motility changes

The HoloMonitor® Cell Motility Assay is designed to explore the average motility of cells in a population and is ideal for studies investigating how various treatments, drug candidates, or environments, influence cell movement over time. Analyze long-term cellular movement when using your standard cell growth media and environment — without labeling, staining or phototoxicity.

Captures and automatically presents speed and distance

The HoloMonitor App Suite software automatically analyzes and presents motility data in terms of speed kinetics, i.e. average cell speed over time, and accumulated mean distance, at each time point. Note that the result presentation is immediate and progresses as the experiment proceeds.

The HoloMonitor Cell Motility Assay automatically presents motility data.

The software automatically presents cell motility data for the cell populations. If preferred, all data can easily be exported to Excel for further analysis.

Assessment of kinetic motility of a cell population

  • Designed to explore the motility of a cell population over time.
  • Ideal for detection of differences in motility causes by the investigated drug or environmental condition vs controls.
  • Automatically calculates and presents  kinetic motility data in terms of mean speed of all cells in the population + accumulated mean distance at each time point.

Experiments set up using App Suite software can easily be re-analyzed to generate results for another assay type. For example, for a motility experiment, proliferation results can be achieved from the same experimental data.

After imaging the undestroyed cells, or the supernatant, can be used again for additional analysis using other methods.

Motility and migration studies of single cells, or sub-populations of cells, can be performed using the Single-cell Tracking software.

Anette Gjörloff Wingren, Malmö University

HoloMonitor provides methodology for label-free imaging of living cells. We use HoloMonitor for studying the effect of drugs on cell morphology, viability, death and motility of cancer cells.

Prof. Anette Gjörloff Wingren

Faculty of Health and Society, Malmö University