HoloMonitor Technology

Label-free live cell imaging and analysis for cell population studies by tracking and quantifying individual cells over time — a technical explanation.

HoloMonitor M4 with HoloMonitor logo

The HoloMonitor® label-free live cell imaging system is based on the principle of quantitative phase imaging, enabling non-invasive visualization and quanti­fication of living cells without compro­mising cell integrity. Here we describe the rationale and advantages of using quanti­tative phase imaging for live cell kinetic analysis of cellular events — explaining the power of live cell time-lapse cytometry and how cells are made visible without labels or stains.

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Label-free Live Cell Imaging

The HoloMonitor label-free live cell imaging system is based on the principle of quanti­tative phase imaging, enabling non-invasive visualization and quanti­fication of living cells without compro­mising cell integrity.
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3D Live cell image of Jimt-1 cells

Quantitative Phase Imaging

Quantitative phase imaging (QPI) provides both quantitative and beautiful images of living cells, transforming phase micro­scopy into a quantitative tool for detailed live cell analysis.
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A quantitative phase image of a cell and the hologram it was created from

Holographic Microscopy

Holographic microscopy is the most common form of quanti­tative phase imaging. The HoloMonitor® live cell time-lapse cytometers employ holographic micro­scopy to allow non-invasive visualization and quanti­fication of living cells without compro­mising cell integrity.
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HoloMonitor App Suite software

Time-lapse Cytometry

Time-lapse cytometry allow non-invasive visualization and analysis of live cell populations by tracking and quantifying individual cells.
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