Malmö University

PHI and Malmö University have a long-standing collaboration, dating back to 2008. The collaboration has resulted in several peer reviewed publications and a doctoral thesis. In late 2016, the European Commission granted 2.1 million euro to GlycoImaging – a joint cancer research project to develop improved methods for clinically diagnosing cancer.

Current methods for diagnosing cancer primarily focus on the proteins associated with cancer. However, there is increasing evidence that carbohydrates play an important role in the development and pro­gression of malignant cancer. Current methods use and rely on antibodies created by living organisms. These natural antibodies, however, are not sufficiently specific to accurately detect and image carbohydrates.

The GlycoImaging project is coordinated by Malmö University and commercialized by PHI. Additional partners are Bundesanstalt für Materialforschung und Prüfung (Germany’s federal technology research institute), Umeå, Copenhagen and Turku University.

Anette Gjörloff Wingren, Malmö University

Oncology research and diagnostics are in need of low-cost and robust probes to detect carbohydrates. The goal of the GlycoImaging project is to meet this need by combining specific carbohydrate probes – in the form of molecular imprinted polymers or ‘plastic antibodies’ – with holographic microscopy.

Prof. Anette Gjörloff Wingren

Faculty of Health and Society, Malmö University

Presentations

Popular lecture on cancer research by Prof. Anette Gjörloff Wingren 2016 (in Swedish).

A short presentation of GlycoImaging by Prof. Anette Gjörloff Wingren (in Swedish).

The GlycoImaging video (in Swedish).

Interviews and News

Peer Reviewed Articles and Book Chapters

Featured Applications

Label-free Cell Cycle Analysis

Live cell imaging cytometry of antibody captured suspension cells

Location

Faculty of Health and Society,
Malmö University
Jan Waldenströms gata 25, AS:F502
205 06 Malmö, Sweden

The Partnerships

  • Lund University Banner

    Lund University Cancer Centre

    The early HoloMonitor development began at Lund University. The relationship between Lund University and PHI has since evolved into partnerships with several research groups.

  • Uppsala University banner

    Uppsala University

    Supported by PHI, scientists at Uppsala University apply state of the art artificial intelligence on its very source of inspiration — cell biology.

  • UCSF Banner

    UCSF

    University of California in San Francisco, Gladstone Institutes and PHI jointly operate San Francisco’s Holographic Imaging Cytometry Center of Excellence.

  • NIA Banner

    National Institute on Aging

    In pursuit of making novel research tools available to National Institute on Aging and the medical research community in general, NIA and PHI are collaborating to develop a fluorescence module to PHI’s HoloMonitor.

  • Gladstone Banner

    Gladstone Institutes

    Gladstone Institutes, UCSF and PHI jointly operate San Francisco’s Holographic Imaging Cytometry Center of Excellence.

  • Commencement at University of Utah

    Huntsman Cancer Institute

    Supported by PHI, Dr. Robert Judson-Torres and his team at Huntsman Cancer Institute aim to develop methods to quantify the phenomena known as epithelial-mesenchymal transition (EMT).

  • Northeastren University banner

    Northeastern University

    The joint program of excellence between Northeastern University and PHI began in late 2014. Since then HoloMonitor technology has rapidly established itself as a technology of choice for label-free kinetic cellular analysis.