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β-Nitrostyrene 1 derivatives attenuate LPS-mediated acute lung injury via the 2 inhibition of neutrophil-platelet interactions and NET release

Authors: Yao-Wen Chang, Ching-Ping Tseng, Chih-Hsun Lee, Tsong-Long Hwang, Yu-Li Chen, Mei-Tzu Su, , Kowit-Yu Chong, Ying-Wei Lan, Chin-Chung Wu, Kung-Ju Chen, Fen-Hua Lu, Hsiang-Ruei Liao, Chuen Hsueh, Pei-Wen Hsieh

Journal: American Journal of Physiology-Lung Cellular and Molecular Physiology (2018)

Institution: Chang Gung University

Research Areas: Inflammation

Cell Lines: Neutrophils

Summary: Time-lapse videos and cell morphology images were recorded with a HoloMonitor M4 to assess the effects of the compound on neutrophil-platelet interaction and activation

Keywords: HoloMonitor M4, Cell morphology, Acute lung injury (ALI), β-nitrostyrene derivatives lipopolysaccharide, Neutrophil extracellular trap, Neutrophil-platelet aggregates, Acute respiratory distress syndrome (ARDS)

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