Adipocytes Migration is Altered Through Differentiation
Microscopy and Microanalysis (2019)
Cell Line: 3T3-L1 (Mouse embryonic preadipocytes)
Research Area: Cell Research
Conclusions: Preadipocyte differentiation from elongated structures to rounded adipocytes is adipogenesis. During the process cell cytoskeleton undergoes changes, which in turn alterate single-cell motility. In this work M. Lusting with colleagues for the first time evaluate differences between the motility of nondifferenciated preadipocytes and differentiated mature adipocytes using hologprahic imaging. Authors have used HoloMonitor M4 to show that preadipocytes move faster and further than adipocytes, idicating that cell cytoskeleton is altered during cell differentiation.