Customer Publication

Alkyl-carbon chain length of two distinct compounds and derivatives are key determinants of their anti-Acanthamoeba activities

Authors: R. Mooney et al.

Journal: Scientific Reports (2020)

Institution: University of the West of Scotland

Research Areas: Parasitic infections

Cell Lines: Acanthamoeba castellanii (Amobea)

Summary: Acanthamoeba are free-living protists, who have opportunistic tendencies. Thus, they can affect the skin, cause severe cornea infections, or in rare cases lead to death. If Acanthamoeba damage the cornea, it can lead to sight loss. Consequently, in this publication, R. Moorey with colleagues, have studied how two molecules affect A. castellani trophozoites and showed that these molecules can be useful for preventing amoeba cornea infections, i.e. by formulating them into contact lens solution. In this study, authors have used HoloMonitor M4 to characterize how the treatment affects A. castellanii morphology: area, perimeter, and volume.

Keywords: HoloMonitor M4, Cell morphology, quaternary ammonium compounds

Read the article …

Phase Holographic Imaging PHI AB
Skiffervägen 48
224 78 Lund
Sweden
+46 46 38 60 80
info@phiab.se

Phase Holographic Imaging PHI Inc.
265 Franklin Street Suite 1702
Boston, MA 02110
USA
+1 617-963-5150
info@phiab.com

Invoicing

VAT: SE556542781101
faktura@phiab.se

Securities Identification

ISIN: SE0005504636
LEI: 549300JZR79QYESM6296

HoloMonitor® is a registered trademark
Copyright © 2012-2021
Phase Holographic Imaging PHI AB

Phase Holographic Image logo in white

PHI Theme 3.12.2