Archives: Customer Publications

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Targeting SASP with FDA-approved agents: minoxidil and diazoxide as potential senomorphic agents in cancer therapy

Authors: Yaprak Dilber Simay Demir et al.

Journal: Turkish Journal of Biochemistry (2025)

Research Areas: Cancer Research

Cell Lines: HeLa

Keywords: HoloMonitor, cell morphology, senomorphic, k+atp channel, ca2+ channel, senescence, cancer, drug repurposing

Bioactive Phenolics from Vinegar–Egg Accelerates Acute Wound Healing by Activation of Focal Adhesion and Mitogen-Activated Protein Kinase Signaling

Authors: Taehoon Oh et al.

Journal: Nutrients (2025)

Research Areas: Cell Research

Cell Lines: MEF

Keywords: HoloMonitor M4, single cell tracking, vinegar-egg, 4-hydroxybenzoic acid, vanillic acid, wound healing, cell motility, migration, cell invasion, focal adhesion kinase (FAK), MAPK, p38

Highly Specific Inhibition of c-Myc Oncogene Expression through Shifting the G-Quadruplex toward a Triplex Structure

Authors: Jolanta Lisowiec-Wąchnicka

Journal: Journal of Medicinal Chemistry (2025)

Research Areas: Chemistry

Keywords: HoloMonitor M4, Cell motility, Biopolymers, Chemical structure, G-Quadruplex

Dissecting Morphological and Functional Dynamics of Non-Tumorigenic and Triple-Negative Breast Cancer Cell Lines Using PCA and t-SNE Analysis

Authors: Almahdi et al.

Journal: Cancer Reports (2025)

Research Areas: Cancer Research

Cell Lines: MCF10A, MDA-MB-231

Keywords: HoloMonitor M4

In situ monitoring of cell adhesion kinetics using label-free optical biosensors: Evaluating anticancer potential and selectivity of natural compounds

Authors: B.Péter et al.

Journal: View (2025)

Research Areas: Drug Discovery

Cell Lines: Hela, MC3T3-E1

Keywords: HoloMonitor M4, cell morphology

Ropivacaine and lidocaine at clinically relevant concentrations suppress proliferation and migration of ovarian cancer cells and induce morphological alterations

Authors: J.Hayden et al.

Journal: Advances in Medical Sciences (2025)

Research Areas: Cancer Research

Cell Lines: SKOV-3, SW-626 and CA-OV-3

Keywords: HoloMonitor M4, cell morphology, ropivacaine, idocaine, ovarian cancer, cell proliferation, cell migration, apoptosis, cell motility

Cells prioritize the regulation of cell mass density

Authors: J. Fu et al.

Journal: Science advances (2025)

Research Areas: Cell Biology

Cell Lines: NIH3T3, HT1080, T47D and Hs578

Keywords: HoloMonitor M4, Cell mass

Modified Nucleotides in Bifunctional Antisense Oligonucleotides: Exploring their Anticancer Potential

Authors: N. Bartys et al.

Journal: ChemMedChem (2025)

Research Areas: Cancer Research

Cell Lines: SKOV-3

Keywords: HoloMonitor M4, cell proliferation, Cell motility, Bifunctional antisense oligonucleotides (BASOs) Alternative splicing PKM1/PKM2 hnRNP A1 Modified nucleotides, phosphorothioate, thiouridine

Changes in Melanoma Cell Morphology Following Inhibition of Cell Invasion by Third-Generation mTOR Kinase Inhibitors

Authors: D. Ciołczyk-Wierzbicka et al.

Journal: International Journal of Molecular Sciences (2025)

Research Areas: Cancer Research

Keywords: HoloMonitor M4, cell morphology, wound healing, cell motility, cell invasion, mTOR protein kinase inhibitors, melanoma

Unraveling Ammonia-Induced Brain Endothelial Senescence: Role of miRNA-183-5p

Authors: K. Orzeł-Gajowik et al.

Journal: Antioxidants & Redox Signaling (2025)

Research Areas: Cell research

Cell Lines: RBE4

Keywords: HoloMonitor M4, cell proliferation, cell motility, hyperammonemia, brain endothelial cells, cellular senescence, miR-183-5p, senescence-associated β-galactosidase, p16, p21, cerebrovascular density, RBE4, blood-brain barrier, endothelial dysfunction

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