Customer Publication

Breast cancer cell line toxicity of a flavonoid isolated from Baccharis densiflora

Authors: Wendy Soria Sotillo, Santiago Tarqui, Xiaoli Huang, Giovanna Almanza, Stina Oredsson

Journal: BMC Complementary Medicine and Therapies (2021)

Institution: Lund university

Research Areas: Cancer research

Cell Lines: JIMT-1 (breast cancer cell)

Summary: Flavonoids are compounds of interest in the search for new anti-cancer therapies. Sotillo and her colleagues investigated the toxicity of different methoxyflavones in human breast-derived cell line JIMT-1. Results showed that methoxyflavone sideritoflavone has favorable anti-cancer effects that may be exploited for development to be used in combination with CSC-specific compounds. HoloMonitor M4 was used for cell motility and cell proliferation study.

Keywords: HoloMonitor M4, Cell motility, Cell proliferation, Flavonoids, Sideritoflavone, Breast cancer, Cytotoxicity, Cell cycle, Cell movement, Cancer stem cells

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