Customer Publication

Ca2+ signals, cell membrane disintegration, and activation of tmem16f during necroptosis

Authors: Jiraporn Ousingsawat, Inês Cabrita, Podchanart Wanitchakool, Lalida Sirianant, Stefan Krautwald, Andreas Linkermann, Rainer Schreiber, Karl Kunzelmann

Journal: Cellular and molecular life sciences (2016)

Institution: Universität Regensburg

Research Areas: Cell research

Cell Lines: NIH3T3, HT29 (Mouse embryonic fibroblasts and human colonic carcinoma)

Summary: It is well known that cells swell during necroptosis. However, proper cell volume measurements are still missing. Using HoloMonitor M4 the authors non-invasively measured the cell volume changes associated with necroptosis. The results were confirmed by flow cytometry measurements.

Keywords: HoloMonitor M4, cell death, Ca2+ signaling

Read the article …