Customer Publication

Characterization of a green, temperature activated nano formulation that drives the mechanism of doxorubicin toxicity from apoptosis to ferroptosis

Authors: Farzana Parveen et al.

Journal: AACR Annual Meeting (2022)

Institution: Northeastern University, Boston, MA

Cell Lines: B16F10, U87-MR, MDA-MB-231, MCF-7

Summary: The authors have developed a green, temperature-activated nano formulation (TAN) to deliver doxorubicin to cancer cells. To evaluate the temporal effects of the formulation, they use HoloMonitor® M4 for 4-dimensional imaging (X pos vs. Y pos vs. Time vs. Density). Their conclusion is that the newly developed TAN is highly potent and likely kills cancer cells by inducing ferroptosis.

Keywords: temperature-activated nano formulation, TAN, doxorubicin, ferroptosis

Read the article …

Phase Holographic Imaging PHI AB
Skiffervägen 48
224 78 Lund
Sweden
+46 46 38 60 80
info@phiab.se

Phase Holographic Imaging PHI Inc.
265 Franklin Street Suite 1702
Boston, MA 02110
USA
+1 617-963-5150
info@phiab.com

Invoicing

VAT: SE556542781101
faktura@phiab.se

Securities Identification

ISIN: SE0005504636
LEI: 549300JZR79QYESM6296

HoloMonitor® is a registered trademark
Copyright © 2012-2021
Phase Holographic Imaging PHI AB

Phase Holographic Image logo in white

PHI Theme 3.12.2