Dermatan Sulfate Is Involved in the Tumorigenic Properties of Esophagus Squamos Cell Carcinom

A. Martin et al.

Cancer Research (2012)

Institution: Lund university, Sweden

Cell Line: TE1 (Human squamous cell carcinoma of the esophagus)

Research Area: Cancer research

Tags: HoloMonitor, Cell morphology

Conclusions: Chondroitin and dermatan sulfate proteoglycans, which occur both in the matrix and at the cell surface, play important roles in thetumorgenic processes. The unique feature that distinguishes DS from CS is the presence of iduronic acid (IdoA) in DS. IdoA in DS influences tumorigenesis by affecting cancer cell behavior

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