Edaravone Protects Against Methylglyoxal-induced Barrier Damage in Human Brain Endothelial Cells
Journal: PLOS ONE (2014)
Institution: Hungarian Academy of Sciences
Research Areas: Drug development
Cell Lines: hCMEC/D3 (Human brain endothelial cells)
Summary: Using holographic microscopy for label-free analysis of living cells, visualized for the first time the kinetics of morphological changes caused by methylglyoxal. The morphology data confirmed that edavarone completely prevented methylglyoxal-induced changes in morphology and detachment of cells.