Enhanced Cytotoxicity of Folic Acid-targeted Liposomes Co-loaded With C6 Ceramide and Doxorubicin: in Vitro Evaluation on HeLa, A2780-ADR and H69-AR Cells
Journal: Molecular pharmaceutics (2015)
Institution: Northeastern University
Research Areas: Cancer research, Drug development
Cell Lines: HeLa (Human cervical cancer)
Summary: Using holomonitor M4, it was found that FA-(C6+Dox)-LP treated hela cells underwent rapid progression to apoptosis (cell suicide) after 21 hours, as evidenced by a drastic drop in cell area after loss of cell membrane integrity.