Exosomes derived from mesenchymal stem cells repair a Parkinson’s disease model by inducing autophagy
Journal: Cell Death and Disease (2020)
Institution: Hebei University of Chinese Medicine
Research Areas: Stem cell research
Cell Lines: hucMSC (Human umbilical cord mesenchymal stem cells)
Summary: Human umbilical cord mesenchymal stem cells (hucMSC) can provide neuroprotection in neurodegenerative diseases, such as Parkinson's disease, treatments. However, at the moment, hucMSC applications are limited due to various reasons. In this study, H.-X. Chen with colleagues has shown that Exosomes derived from hucMSC have the potential for effective Parkinson's disease treatment because they can pass the Brain-Blood barrier. Here, HoloMonitor M4 was used to characterize hucMSC cell proliferation and helped to characterize hucMSC self-renewal and reproductive abilities.