Exosomes derived from mesenchymal stem cells repair a Parkinson’s disease model by inducing autophagy
Cell Death and Disease (2020)
Institution: Hebei University of Chinese Medicine, China
Cell Line: hucMSC (Human umbilical cord mesenchymal stem cells)
Research Area: Stem cell therapy
Conclusions: Human umbilical cord mesenchymal stem cells (hucMSC) can provide neuroprotection in neurodegenerative diseases, such as Parkinson’s disease, treatments. However, at the moment, hucMSC applications are limited due to various reasons. In this study, H.-X. Chen with colleagues has shown that Exosomes derived from hucMSC have the potential for effective Parkinson’s disease treatment because they can pass the Brain-Blood barrier. Here, HoloMonitor M4 was used to characterize hucMSC cell proliferation and helped to characterize hucMSC self-renewal and reproductive abilities.