Fibroblasts Cultured on Nanowires Exhibit Low Motility, Impaired Cell Division, and Dna Damage

H. Persson et al.

Small (2013)

Institution: Lund University, Sweden

Cell Line: L929 (Mouse fibroblasts)

Research Area: Nanomaterials

Tags: HoloMonitor M3, cell motility, cell proliferation, cell division, DNA damage

Conclusions: Fibroblast behaviour on vertical nanowire arrays was investigated using the Holo­Monitor M3. It was shown that cell motility and proliferation rate are reduced on nanowires. Fibroblasts cultured on long nanowires exhibit failed cell division, DNA damage, increased ROS content and respiration.

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