Customer Publication

Hypoxia-inducible Factor-1 Alpha Is Involved in Rip-induced Necroptosis Caused by in Vitro and in Vivo Ischemic Brain Injury

Authors: Xiao-Sa Yang, Tai-Long Yi, Sai Zhang, Zhong-Wei Xu, Ze-Qi Yu, Hong-Tao Sun, Cheng Yang, Yue Tu, Shi-Xiang Cheng

Journal: Scientific Reports (2017)

Institution: Tianjin Key Laboratory of Neurotrauma Repair

Research Areas: Neuroscience

Cell Lines: HT-22 (Murine hippocampal neuronal)

Summary: These findings indicate that necroptosis contributes to ischemic brain injury induced by OGD and MCAO and implicate HIF-1α, RIP1, RIP3, and MLKL in necroptosis.

Keywords: HoloMonitor M4, Cell viability, Necroptosis, Ischemic brain injury

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