Hypoxia-inducible Factor-1 Alpha Is Involved in Rip-induced Necroptosis Caused by in Vitro and in Vivo Ischemic Brain Injury

X. Yang et al.

Scientific reports (2017)

Institution: Logistics University of PAP, China

Cell Line: HT-22 (Murine hippocampal neuronal)

Research Area: Ischemic brain injury

Tags: HoloMonitor M4, Cell viability, Necroptosis

Conclusions: These findings indicate that necroptosis contributes to ischemic brain injury induced by OGD and MCAO and implicate HIF-1α, RIP1, RIP3, and MLKL in necroptosis.

Read the article …