Hypoxia-inducible Factor-1 Alpha Is Involved in Rip-induced Necroptosis Caused by in Vitro and in Vivo Ischemic Brain Injury
Scientific reports (2017)
Institution: Logistics University of PAP, China
Cell Line: HT-22 (Murine hippocampal neuronal)
Research Area: Ischemic brain injury
Conclusions: These findings indicate that necroptosis contributes to ischemic brain injury induced by OGD and MCAO and implicate HIF-1α, RIP1, RIP3, and MLKL in necroptosis.