Customer Publication

Imidazole Compounds for Protecting Choroidal Endothelial Cells from Complement Injury

Authors: S. Zeng et al.

Journal: Scientific Reports (2018)

Institution: University of Iowa

Research Areas: Aging

Cell Lines: RF/6A (Promate endothelial cells (nonhuman))

Summary: AMD (age-related macular degeneration) is a common and serious eye disease, affecting mostly elderly people. The authors found two drug candidates that seemed to protect endothelial cells from the kind of complement-induced injury and cell death seen in AMD. Using HoloMonitor M4 is was shown that drug pretreatment reduced the cell surface roughness, thus indicating improved cell health.

Keywords: HoloMonitor M4, Cell death, Age-related macular degeneration

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