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In Situ Morphological Assessment of Apoptosis Induced by Phaleria Macrocarpa (Boerl.) Fruit Ethyl Acetate Fraction (Pmeaf) in Mda-mb-231 Cells by Microscopy Observation

Authors: Nowroji Kavitha, Yeng Chen, Jagat R. Kanwar, Sreenivasan Sasidharan

Journal: Biomedicine & Pharmacotherapy (2017)

Institution: Universiti Sains Malaysia

Research Areas: Cytotoxicity

Cell Lines: MDA-MB-231, Vero (Human mammary carcinoma cell lines and green monkey kidney epithelial cells (non-cancerous cells))

Summary: The purpose of the study was to determine the cytotoxic effect of P. macrocarpa fruit ethyl acetate fraction (PMEAF) by using various conventional and modern microscopy techniques. The results indicate that PMEAF is a potential anticancer agent and a candidate for developing more potent anticancer drugs.

Keywords: HoloMonitor M3, Apoptosis, CyQUANT assay, Electron microscopy, Holography image, Medicinal plant

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