In Situ Morphological Assessment of Apoptosis Induced by Phaleria Macrocarpa (Boerl.) Fruit Ethyl Acetate Fraction (Pmeaf) in Mda-mb-231 Cells by Microscopy Observation

N. Kavitha et al.

Biomedicine & Pharmacotherapy (2017)

Institution: Universiti Sains Malaysia, Malaysia

Cell Line: MDA-MB-231, Vero (Human mammary carcinoma cell lines and green monkey kidney epithelial cells (non-cancerous cells))

Research Area: Apoptosis

Tags: HoloMonitor M3, Apoptosis, CyQUANT assay, Electron microscopy, Holography image, Medicinal plant

Conclusions: The purpose of the study was to determine the cytotoxic effect of P. macrocarpa fruit ethyl acetate fraction (PMEAF) by using various conventional and modern micro­scopy techniques. The results indicate that PMEAF is a potential anticancer agent and a candidate for developing more potent anticancer drugs.

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