Customer Publication

Influence of salinomycin treatment on division and movement of individual cancer cells cultured in normoxia or hypoxia evaluated with time-lapse digital holographic microscopy

Authors: Sofia Kamlund,Daniel Strand,Birgit Janicke,Kersti Alm, Stina Oredsson

Journal: Cell Cycle (2017)

Institution: Lund University

Research Areas: Cancer research

Cell Lines: JIMT-1, L929, MCF-7 (JIMT and MCF-7 human breast cancer cells)

Summary: Digital holographic microscopy was used for longitudinal cell tracking of individual cells. Various parameters were investigated and the results suggest that EMT (epithelial to mesenchymal transision) and MET (mesenchymal to epithelial transission) can be investigated using this method.

Keywords: HoloMonitor M4, Digital holography, Cell cycle, Cell migration, Longitudinal tracking of individual cells, Time-lapse, Normoxiahy, Poxia, Salinomycin

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