Customer Publication

iTRAQ-Based Quantitative Proteomics Reveals the New Evidence Base for Traumatic Brain Injury Treated with Targeted Temperature Management

Authors: Shi-Xiang Cheng, Zhong-Wei Xu, Tai-Long Yi, Hong-Tao Sun, Cheng Yang, Ze-Qi Yu, Xiao-Sa Yang, Xiao-Han Jin, Yue Tu, Sai Zhang

Journal: Neurotherapeutics (2017)

Institution: Tianjin Key Laboratory of Neurotrauma Repair

Research Areas: Neuroscience

Cell Lines: SH-SY5Y and HT-22 (Human neuroblastoma cells and mouse hippocampal cells)

Summary: Targeted temperature management (TTM) modulation on traumatic brain injury (TBI). HoloMonitor was used to analyze cell area and cell volume after exposure of cells to hypothermia or normothermia.

Keywords: HoloMonitor M4, Targeted temperature management, Traumatic brain injury, Proteomics, Isobaric tags for relative and absolute quantitation, Cerebrospinal fluid

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