Label-free optical biosensor for real-time monitoring the cytotoxicity of xenobiotics: A proof of principle study on glyphosate

Authors: E Farkasa et al.

Journal: Journal of Hazardous Materials (2018)

Institution: Hungarian Academy of Science

Research Areas: Cytotoxicity

Cell Lines: MC3T3-E1 (Mammalian osteoblastic cell line)

Summary: In the present work, the herbicide product Roundup Classic, its formulant (POEA) and its active ingredient (glyphosate) were studied on a mammalian osteoblastic cell line (MC3T3-E1) model using the optical biosensor Epic BT. Cell viability was monitored by HoloMonitor M4 by analyzing three-dimensional morphological structures of the cells.

Keywords: HoloMonitor M4, Cytotoxicity Cell morphology, Label-free biosensor, Resonant waveguide grating, Glyphosate, Polyethoxylated tallow amine

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