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MicroRNA-362-3p Inhibits Migration and Invasion via Targeting BCAP31 in Cervical Cancer
Journal: Frontiers in Molecular Biosciences (2020)
Institution: The Fourth Military Medical University
Research Areas: Cancer research
Cell Lines: HeLa (Cervical cancer cell line)
Summary: MicroRNAs play one of the key roles in cervical cancer metastasis. Thus, in this study, S. Yang with colleagues have investigated the miR-362-3p targeting mechanism and effect. Authors have shown that miR-263-3p plays an important role in cervical cancer metastasis, as it regulates cell migration and motility by directly targeting BCAP31 protein. Hence, making miR-263-3p a potential target for cervical cancer treatment. Here, HoloMonitor M4 was used to characterize HeLa cell migration and motility after transfection.