Non-invasive, quantitative assessment of the morphology of γ-irradiated human mesenchymal stem cells and periosteal cells using digital holographic microscopy
Journal: International Journal of Radiation Biology (2016)
Institution: Niigata University
Research Areas: Stem cell therapy
Cell Lines: MSC-AT, MSC-BM (Mesenchymal stem cells derived from adipose tissue (MSC-AT) and bone marrow (MSC-BM))
Summary: To assure the quality of cells to be used in cell therapy, we examined the applicability of digital holographic microscopy (DHM) for non-invasive, quantitative assessment of changes in cell morphology. Cell morphological parameters (e.g. cell volume) monitored by HoloMonitor could be useful and more stable than the DNA damage markers currently used.