Ouabain suppresses the growth and migration abilities of glioma U‑87MG cells through inhibiting the Akt/mTOR signaling pathway and downregulating the expression of HIF‑1α
Journal: Molecular Medicine Reports (2017)
Institution: Tianjin Key Laboratory of Neurotrauma Repair
Research Areas: Cancer Research
Cell Lines: U87MG cells (Human glioblastoma)
Summary: The present study revealed that ouabain intervention inhibited U‑87MG cell viability and cell motility in a dose‑dependent manner, suggesting that ouabain promoted the apoptosis of U87‑MG cells. HoloMonitor was used to analyze cell motility, cell count and to study the 3D cell structure.