Poloxamer Bioadhesive Hydrogel for Buccal Drug Delivery: Cytotoxicity and Trans-epithelial Permeability Evaluations Using Tr146 Human Buccal Epithelial Cell Line
International journal of pharmaceutics (2015)
Institution: Paris Descartes University, France
Cell Line: Tr146 (Human buccal epithelial cell line)
Research Area: Drug development
Conclusions: The assessment of cell viability (MTT, Alamar Blue), membrane integrity (Neutral Red), and apoptosis assay (Hoechst 33342), were performed and associated with holomonitor M3 analysis.