Supervised Classification of Etoposide-treated in Vitro Adherent Cells Based on Noninvasive Imaging Morphology
Journal of Medical Imaging (2017)
Institution: Malmö University, Sweden
Cell Line: DU-145 (Prostate cancer cells)
Research Area: Image-based analysis, cell classification
Conclusions: The morphological changes observed occur before and at lower concentrations than a reduction in cell metabolic activity or viability. Three classifiers are compared and we report a best case sensitivity of 88% and specificity of 94% for classification of cells as treated/untreated.