Synthesis, characterization and in vitro and in vivo photodynamic activities of a gallium(iii) tris(ethoxycarbonyl)corrole

Z. Zhang et al.

Dalton Transactions 2017 (2017)

Institution: South China University of Technology, China

Cell Line: A549 (Human lung carcinoma cells)

Research Area: Photo-cytotoxicity; photodynamic therapy (PDT)

Tags: HoloMonitor M3, Cell morphology, apoptosis

Conclusions: After illumination and treatment with 1-Ga, A549 cells exhibited characteristics typical of apoptosis, spherical shape of the cells, chromatin condensation, and nuclear membrane irregularity. After incubation for 1 h, the authors found that the cells started to contract, the area decreased and the thickness increased.

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