Customer Publication

Synthesis, Characterization and in Vitro and in Vivo Photodynamic Activities of a Gallium(III) Tris(Ethoxycarbonyl)corrole

Authors: Zhao Zhang, Hua-Hua Wang, Hua-Jun Yu, Yu-Zhen Xiong, Hai-Tao Zhang, Liang-Nian Ji, Hai-Yang Liu

Journal: Dalton Transactions (2017)

Institution: South China University of Technology

Research Areas: Cancer research

Cell Lines: A549 (Human lung carcinoma cells)

Summary: After illumination and treatment with 1-Ga, A549 cells exhibited characteristics typical of apoptosis, spherical shape of the cells, chromatin condensation, and nuclear membrane irregularity. After incubation for 1 h, the authors found that the cells started to contract, the area decreased and the thickness increased.

Keywords: HoloMonitor M3, Cell morphology, Apoptosis, Photo-cytotoxicity, photodynamic therapy (PDT)

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