Synthesis, characterization and in vitro and in vivo photodynamic activities of a gallium(iii) tris(ethoxycarbonyl)corrole
Dalton Transactions 2017 (2017)
Institution: South China University of Technology, China
Cell Line: A549 (Human lung carcinoma cells)
Research Area: Photo-cytotoxicity; photodynamic therapy (PDT)
Conclusions: After illumination and treatment with 1-Ga, A549 cells exhibited characteristics typical of apoptosis, spherical shape of the cells, chromatin condensation, and nuclear membrane irregularity. After incubation for 1 h, the authors found that the cells started to contract, the area decreased and the thickness increased.