Tau Phosphorylation and Amyloid-β Deposition in the Presence of Formaldehyde
Journal: Formaldehyde and Cognition (2017)
Institution: University of Chinese Academy of Sciences
Research Areas: Alzheimer’s disease
Summary: Mechanisms related to Alzheimer’s disease (AD). Formaldehyde is shown to be a strong trigger of Aβ deposition and Tau phosphorylation, so that the dysmetabolism of endogenous formaldehyde should occur in the early stage of AD as formaldehyde disturbs nervous system in different pathways and in diverse manners.