Customer Publication

The anti-tumor efficacy of 20(S)-protopanaxadiol, an active metabolite of ginseng, according to fasting on hepatocellular carcinoma

Authors: W. Li et al.

Journal: Journal of Ginseng Research (2021)

Institution: Binzhou Medical University

Research Areas: Oncology

Cell Lines: HepG2, H22 (Human hepatocarcinoma cells; mouse hepatocellular carcinoma (HCC) cell line)

Summary: 20(S)-protopanaxadiol (20(S)-PPD), one of the main active metabolites of ginseng, performs a broad spectrum of anti-tumor effects. The aims are to search out new strategies to enhance the anti-tumor effects of natural products, including 20(S)-PPD. Here, the effects of fasting combined with 20(S)-PPD on hepatocellular carcinoma growth, apoptosis, migration, invasion, and cell cycle were explored. Results showed that fasting significantly sensitized HCC cells to 20(S)-PPD in vivo and in vitro. These data indicated that dietary restriction could be one of the potential strategies of Chinese medicine or its active metabolites against hepatocellular carcinoma. In addition, HoloMonitor M4 is used to study cell proliferation and single-cell tracking.

Keywords: HoloMonitor M4, cell proliferation, single cell track ,20(S)-protopanaxadiolfasting-mimickingintermittent fasting, hepatocellular carcinoma

Read the article …

Phase Holographic Imaging PHI AB
Skiffervägen 48
224 78 Lund
+46 46 38 60 80

Phase Holographic Imaging PHI Inc.
265 Franklin Street Suite 1702
Boston, MA 02110
+1 617-963-5150


VAT: SE556542781101

Securities Identification

ISIN: SE0005504636
LEI: 549300JZR79QYESM6296

HoloMonitor® is a registered trademark
Copyright © 2012-2021
Phase Holographic Imaging PHI AB

Phase Holographic Image logo in white

PHI Theme 3.12.2