Customer Publication

Tuning Anti-Biofilm Activity of Manganese(II) Complexes: Linking Biological Effectiveness of Heteroaromatic Complexes of Alcohol, Aldehyde, Ketone, and Carboxylic Acid with Structural Effects and Redox Activity

Authors: A. Wawrzycka et al.

Journal: International Journal of Molecular Sciences (2021)

Institution: Jan Kochanowski University of Kielce

Research Areas: Antibiotics

Cell Lines: VH10 (Human foreskin fibroblasts)

Summary: Antibiotic resistance is a rising issue worldwide and becoming one of the most challenging problems in our time. Thus alternative antimicrobial therapies are urgently required. In this study, the authors have used new manganese (II) complex to target bacterial pathogen by inhibiting the biofilm formation and other antibacterial activity in the primary human fibroblast (VH10) model. HoloMonitor M4 was used to count cell numbers after various treatments to study cell viability.

Keywords: HoloMonitor M4, cell counter, manganese(II) complexes, crystal structure, HS surface analysis, antibacterial and anti-biofilm activity, structure–activity relationship, inhibition effect of catalas

Read the article …

Phase Holographic Imaging PHI AB
Skiffervägen 48
224 78 Lund
Sweden
+46 46 38 60 80
info@phiab.se

Phase Holographic Imaging PHI Inc.
265 Franklin Street Suite 1702
Boston, MA 02110
USA
+1 617-963-5150
info@phiab.com

Invoicing

VAT: SE556542781101
faktura@phiab.se

Securities Identification

ISIN: SE0005504636
LEI: 549300JZR79QYESM6296

HoloMonitor® is a registered trademark
Copyright © 2012-2021
Phase Holographic Imaging PHI AB

Phase Holographic Image logo in white

PHI Theme 3.12.2