Unravelling the role of trophoblastic-derived extracellular vesicles in in regulatory T cell differentiation

Á. Kovács et al.

International Journal of Molecular Sciences (2019)

Institution: Semmelweis University, Hungary

Cell Line: Regulatory T cells (Primary human immune suppressive cells)

Research Area: Cell Research

Tags: HoloMonitor M4, cell migration and motility, extracellular vesicles, EVs; HSPE1, miRNA, C19MC, regulatory T cells

Conclusions: A. F. Kovacs et al has studied de novo differentiation of regulatory T cells by trophoblast-derived extracellular vesicles. Authors show that HSPE1 is a useful marker of Treg subtype characterization and have an important role in Treg cell expansion in vitro. Authors have employed HoloMonitor M4 to study Treg cell viability and showed positive migratory and motility capacity.

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