Archives: Customer Publications

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A novel ROCK inhibitor: off-target effects of metformin

Authors: Aysun Özdemir et al.

Journal: Turkish Journal of Biology (2021)

Research Areas: Drug research

Cell Lines: HeLa and MCF-7

Keywords: HoloMonitor M4, cell morphology, connectivity MAP, Rho kinase, metformin, off-target effect, oral antidiabetics

Monobutyl phthalate can induce autophagy and metabolic disorders by activating the ire1a-xbp1 pathway in zebrafish liver

Authors: Ying Zhang et al.

Journal: Journal of Hazardous Materials (2021)

Research Areas: Toxicology

Cell Lines: Zebra fish (AB strain) liver cells

Keywords: HoloMonitor M4, cell morphology, ER stress, UPR pathway, Autophagy, Glucose metabolism, Lipid metabolism, Chemical toxicity

Snail Overexpression Alters the microRNA Content of Extracellular Vesicles Released from HT29 Colorectal Cancer Cells and Activates Pro-Inflammatory State In Vivo

Authors: Izabela Papiewska-Pająk et al.

Journal: Cancers (2021)

Research Areas: Cancer research

Cell Lines: HT-29

Keywords: HoloMonitor M4, cell motility, snail transcription factor, extracellular vesicles, colon cancer, pre-metastatic niche

Cellular Effects of Cystatins

Authors: Hunaiti et al.

Research Areas: Cancer research

Keywords: Doctoral thesis, cancer and oncology, cystatin c, cystatin d, galectin-1, puncta assay, holomonitor, cancer cells, apoptosis, cathepsin c

Monoclonal antibody 2C5 specifically targets neutrophil extracellular traps

Authors: Livia P. Mendes et al.

Journal: mAbs (2020)

Research Areas: Cell Research

Cell Lines: HL-60

Keywords: HoloMonitor M4, cell morphology, neutrophil extracellular traps, monoclonal antibody, active targeting2C5, microfluidic study

Targeted inhibition of ERα signaling and PIP5K1α/Akt pathways in castration‐resistant prostate cancer

Authors: Julius Semenas et al.

Journal: Molecular Oncology (2020)

Research Areas: Cancer research

Cell Lines: PC-3

Keywords: HoloMonitor M4, Cell morphology, castration-resistant prostate cancer, estrogen receptor, PI3K/AKT pathway andtamoxifen, PIP5K1a, targeted therapy

Efficient and crucial quality control of HAP1 cell ploidy status

Authors: Tobias B. Beigl et al.

Journal: Biology Open (2020)

Research Areas: Cell Research

Cell Lines: HAP1

Keywords: HoloMonitor M4, Single cell tracking, Cell morphology and cell movements, HAP1, Near-haploid human cell line, CRISPR/Cas9, Gene editing, Clustered palindromic repeats, Cas9 enzyme, Cell phenotype analyses, Microscopy genetic disease cell model, Cell culture quality control

Smart drug combinations for cervical cancer: dual targeting of Bcl-2 family of proteins and aurora kinases

Authors: Jacklyn Yumol et al.

Journal: Am J Cancer Res (2020)

Research Areas: Cancer research

Cell Lines: HeLa

Keywords: HoloMonitor M4, cell morphology, HPV, aurora kinase, cervical cancer, alisertib

Exploiting the potential of commercial digital holographic microscopy by combining it with 3D matrix cell culture assays

Authors: Monica Hellesvik et al.

Journal: Scientific Reports (2020)

Research Areas: Method Development

Cell Lines: NCL-H524, U2OS

Keywords: HoloMonitor M4, Cell movements, Cell morphology, Wound Healing, Cell Invasion

SUMOylation of PUM2 promotes the vasculogenic mimicry of glioma cells via regulating CEBPD

Authors: Di Wang et al.

Journal: Clinical and Translational Medicine (2020)

Research Areas: Cancer research

Cell Lines: U251, U373

Keywords: HoloMonitor M4, cell movements, CEBPD, PUM, SUMOylation, UBEI, vasculogenic mimicry

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