Peer-reviewed Publications

Below you will find summaries and links to peer-reviewed publications and book chapters discussing HoloMonitor, its applications and the core technology — digital holographic and quantitative phase imaging (QPI) microscopy.

CDK4/6 inhibitor-mediated cell overgrowth triggers osmotic and replication stress to promote senescence

Authors: Crozier et al.

Journal: Molecular cell (2023)

Research Areas: Cancer Research

Cell Lines: hTERT-RPE1 mRuby-PCNA, hTERT-RPE1-FUCCI, MCF7

Keywords: HoloMonitor M4, cell morphology, cell volume, cell cycle, cell size, palbociclib, p21, Cip1/Waf1, p38, MAPK, DNA damage, p53, rapamycinmTOR, cell growth

Oncogenic signals prime cancer cells for toxic cell overgrowth during a G1 cell cycle arrest

Authors: Foy R et al.

Journal: Molecular cell (2023)

Research Areas: Cancer Research

Cell Lines: RPE, MCF7 and T47D

Keywords: HoloMonitor M4, cell morphology, CDK4/6, oncogenes, cell growth, cell cycle, growth factors, chemotherapy, breast cancer, p53, p21, replication stress

IK Channel-Independent Effects of Clotrimazole and Senicapoc on Cancer Cells Viability and Migration

Authors: Paolo Zuccolini et al.

Journal: International Journal of Molecular Sciences (2023)

Research Areas: Cancer Research

Cell Lines: WM266-4, panc-1

Keywords: HoloMonitor M4, wound healing assay, ik, kca3, 1, kcnn4, cancer, melanoma, pancreatic duct adenocarcinoma (pdac), blockers, clotrimazole, senicapoc

IRE1-mediated degradation of pre-miR-301a promotes apoptosis through upregulation of GADD45A

Authors: Gebert et al.

Journal: Cell Communication and Signaling (2023)

Cell Lines: 16HBE14o

Keywords: HoloMonitor M4, cell morphology assay, cell viability, cell biology, protein-ligand interactions, receptors, cytokines and growth factors

Expression profiles and function prediction of tRNA-derived fragments in glioma

Authors: Wei et al.

Journal: BMC Cancer (2023)

Research Areas: Cancer research

Cell Lines: U87MG, U373MG, U251MG, SVG p12

Keywords: HoloMonitor M4, glioblastoma, single cell analysis, Glioma, tRNA-derived fragment, tRF, Non-coding RNA, S100A11

Pseudogene MAPK6P4-encoded functional peptide promotes glioblastoma vasculogenic mimicry development

Authors: Zhang et al.

Journal: Communications Biology (2023)

Research Areas: Cancer research

Cell Lines: U251, U373, and HEK 293T cells

Keywords: HoloMonitor M4, single cell tracking, cns cancer, phosphorylation, glioblastoma, vasculogenic mimicry

Mast Cell-Mediated Orchestration of Airway Epithelial Responses in Chronic Respiratory Diseases

Authors: Frida Berlin

Journal: Doctoral thesis (2023)

Research Areas: Cell biology

Keywords: HoloMonitor M4, Mast cells, proteases, tryptase, chymase, chronic respiratory diseases, asthma

A novel peptide P1-121aa encoded by STK24P1 regulates vasculogenic mimicry via ELF2 phosphorylation in glioblastoma

Authors: Li et al.

Journal: Experimental Neurology (2023)

Research Areas: Cancer research

Cell Lines: U251, U373, HEK293T, HA

Keywords: HoloMonitor M4, Single cell tracking, glioblastoma STK24P1, P1-121aa, ELF2 Phosphorylation

Polysaccharide-based nano-engineered multilayers for controlled cellular adhesion in label-free biosensors

Authors: Wasilewska et al.

Journal: International Journal of Biological Macromolecules (2023)

Research Areas: Materials Science

Cell Lines: MC3T3-E1

Keywords: HoloMonitor M4, Cell proliferation, Cell morphology, Macroion multilayers, Polysaccharide layers, Label-free biosensors, Streaming potential, OWLS, Resonant waveguide grating, Cell adhesion, Antimicrobial coatings, QCM

Induction of Fungal Secondary Metabolites by Co-Culture with Actinomycete Producing HDAC Inhibitor Trichostatins

Authors: Gwi Ja Hwang et al.

Journal: Journal of microbiology and biotechnology (2023)

Research Areas: Microbiology

Cell Lines: MDA-MB-231 cells

Keywords: HoloMonitor M4, Single cell tracking, co-culture system, fungal cryptic secondary metabolites, structure determination, physical interaction

Mast Cell Tryptase Promotes Airway Remodeling by Inducing Anti-Apoptotic and Cell Growth Properties in Human Alveolar and Bronchial Epithelial Cells

Authors: Frida Berlin et al.

Journal: Cells (2023)

Research Areas: Cell Biology

Cell Lines: BECs, BEAS-2B, AECs, A549

Keywords: HoloMonitor M4, cell proliferation, mast cell, proteases, tryptase, bronchial epithelium, alveolar epithelium, growth factors, anti-apoptosis, airway remodeling, cell growth, par-2

A role for androgen receptor variant 7 in sensitivity to therapy: Involvement of IGFBP-2 and FOXA1

Authors: K.M. Biernacka

Journal: Translational Oncology (2023)

Research Areas: Cancer Research

Cell Lines: LNCaP, 22Rv1, VCaP

Keywords: HoloMonitor M4, cell proliferation, single cell tracking, cell motility, cell division, ARV7, androgen receptor, FOXA1, IGFBP-2, chemotherapy, prostate cancer

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