Peer-reviewed Publications

Below you will find summaries and links to peer-reviewed publications and book chapters discussing HoloMonitor, its applications and the core technology — digital holographic and quantitative phase imaging (QPI) microscopy.

CAT3, a prodrug of 13a(S)-3-hydroxyl-6,7-dimethoxyphenanthro[9,10-b]-indolizidine, circumvents temozolomide-resistant glioblastoma via the Hedgehog signaling pathway, independently of O6-methylguanine DNA methyltransferase expression

Authors: Ming Ji et al.

Journal: OncoTargets and Therapy (2022)

Research Areas: Cancer research

Cell Lines: T98G, U251

Keywords: HoloMonitor M4, cell count, gli inhibitor, chemotherapy, lomeguatrib, xenograft tumor model

Genetic deletion of HPV E7 oncogene effectively regresses HPV driven oral squamous carcinoma tumour growth

Authors: Danyelle Assis Ferreira et al.

Journal: Biomedicine & Pharmacotherapy (2022)

Research Areas: Virus, Cancer research

Cell Lines: SCC2, HEK293T cells

Keywords: HoloMonitor M4, Human papillomavirus, E7, CRISPR, Oral cancer, Aurora kinase

The Multicellular Effects of VDAC1 N-Terminal-Derived Peptide

Authors: Uttpal Anand et al.

Journal: Biomolecules (2022)

Research Areas: Cell research

Cell Lines: PC-3, HeLa, U-87MG, MEC-1, T-Rex-293, MEF

Keywords: HoloMonitor M4, cell morphology, apoptosis, mitochondria, peptide array, protein–protein interaction, voltage-dependent anion channel-1

Reduced Glutathione Decreases Cell Adhesion and Increases Cell Volume

Authors: Alain Géloën et al.

Journal: Archives of Clinical and Biomedical Research (2022)

Research Areas: Cell research

Cell Lines: A549

Keywords: Holomonitor M4, cell morphology, A549, Cell Volume, Cell Adhesion, Glutathione

Mast Cell Proteases Promote Diverse Effects on the Plasminogen Activation System and Wound Healing in A549 Alveolar Epithelial Cells

Authors: Sofia Mogren et al.

Journal: Cells (2022)

Research Areas: Cell research

Cell Lines: A549

Keywords: HoloMonitor M4, wound healing, cell motility, mast cell, tryptase, chymase, alveolar epithelial cells, wound healing, migration, urokinase plasminogen activator receptor

Chronic glucocorticoid exposure accelerates Aβ generation and neurotoxicity by activating calcium-mediated CN-NFAT1 signaling in hippocampal neurons in APP/PS1 mice

Authors: Shixin Ding et al.

Journal: Food and Chemical Toxicology (2022)

Research Areas: Neuroscience

Cell Lines: Primary hippocampal neurons

Keywords: HoloMonitor M4, cell morphology, cell motility, Alzheimer's diseases, Glucocorticoids, Calcium homeostasis disorder, Nuclear factor of activated T cells 1 (NFAT1), Aβ generation

Dipeptidyl peptidase 4 expression is not associated with an activated fibroblast phenotype in idiopathic pulmonary fibrosis

Authors: Måns Kadefors et al.

Journal: Frontiers in Pharmacology (2022)

Research Areas: Pharmacology

Cell Lines: Primary human lung fibroblasts

Keywords: HoloMonitor M4, cell morphology, cell proliferation, cell motility, fibroblast, lung, fibrosis, idiopathic pulmonary fibrosis, dipeptidyl peptidase 4

Cell-substratum and Cell-cell Adhesion Forces and Single-cell Mechanical Properties in Mono- and Multilayer Assemblies From Robotic Fluidic Force Microscopy

Authors: Ágoston G.Nagy et al.

Journal: European Journal of Cell Biology (2022)

Research Areas: Cell Research

Cell Lines: Vero, HeLa

Keywords: HoloMonitor M4, cell morphology, Cell biomechanics, Cell adhesion Forces, Fluidic force microscopy, Cell-cell forces

The TIGD5 gene located in 8q24 and frequently amplified in ovarian cancers is a tumor suppressor

Authors: Yuntao Dai et al.

Journal: Genes to Cells (2022)

Research Areas: Cancer research

Cell Lines: SNU8, SNU119, SKOV3, OVCAR3, K119, HAC2

Keywords: HoloMonitor M4, single cell tracking, cell migration, 8q24, MYC, ovarian cancer, TIGD5, tumor suppressor

Jejuketomycins A and B, polyketide glycosides with cancer cell migration inhibitory activity from Streptomyces sp. KCB15JA15

Authors: Jun-Pil Jang et al.

Journal: RSC Advances (2022)

Research Areas: Cancer research

Cell Lines: PC12, HeLa, A549, MEF, MDA-MB-231

Keywords: HoloMonitor, single cell tracking

Cellular Mechanosensitivity: Validation of an Adaptable 3D-Printed Device for Microindentation

Authors: Giulio Capponi et al.

Journal: Nanomaterials (2022)

Research Areas: Materials of Science

Cell Lines: A1

Keywords: Cell morphology, mechanosensitivity, mechanobiology, mechanotransduction, 3d printing, nanomaterials piezo1

Therapy-Induced Senescent/Polyploid Cancer Cells Undergo Atypical Divisions Associated with Altered Expression of Meiosis, Spermatogenesis and EMT Genes

Authors: Joanna Czarnecka-Herok et al.

Journal: International Journal of Molecular Sciences (2022)

Research Areas: Cancer research

Cell Lines: HCT116, MCF-7

Keywords: sbem scans, cancer, cell senescence, chemotherapy, polyploidization, soma-to-germline transition, senescence escape