Peer-reviewed Publications

Below you will find summaries and links to peer-reviewed publications and book chapters discussing HoloMonitor, its applications and the core technology — digital holographic and quantitative phase imaging (QPI) microscopy.

Cells and Holograms — Holograms and Digital Holographic Microscopy as a Tool to Study the Morphology of Living Cells

Authors: Kersti Alm et al.

Journal: Holography — Basic Principles and Contemporary Applications (2013)

Research Areas: Method development

Keywords: Digital holographic technology

Lipids as Tumoricidal Components of Human Α-lactalbumin Made Lethal to Tumor Cells (Hamlet): Unique and Shared Effects on Signaling and Death

Authors: James C.S. Ho et al.

Journal: J. Of Biological Chemistry (2013)

Research Areas: Cancer research

Cell Lines: A549

Keywords: Holomonitor M3, cell morphology, cancer Biology, Cell Death, Lipids, Lipid Metabolism, Protein Complexes, Protein Folding, HAMLET, Oleate, Oleic Acid, Action of HAMLET

A Unifying Mechanism for Cancer Cell Death Through Ion Channel Activation by Hamlet

Authors: Petter Storm et al.

Journal: PLOS One (2013)

Research Areas: Cancer research

Cell Lines: A549, HeLa, A498

Keywords: HoloMonitor M2, Cell morphology, Carcinoma, Cell death, Ion channels, MAPK signaling cascades, Cell differentiation, Lung and intrathoracic tumors, Cell membranes, Apoptosis, Action of HAMLET

Prevention and Treatment of Colon Cancer by Peroral Administration of Hamlet

Authors: Manoj Puthia et al.

Journal: Gut (2013)

Research Areas: Cancer research

Cell Lines: DLD1

Keywords: HoloMonitor M2, Cell morphology, Action of HAMLET

Low Resolution Solution Structure of Hamlet and the Importance of Its Alpha-domains in Tumoricidal Activity

Authors: James Ho CS et al.

Journal: PLOS ONE (2012)

Research Areas: Cancer research

Cell Lines: A549

Keywords: HoloMonitor M3, cell morphplogy, Oleates, Crystal structure, Lung and intrathoracic tumors, Oleic acid, Small-angle scattering, Carcinoma, Cell death, Protein structure, Action of HAMLET

HAMLET: Functional Properties and Therapeutic Potential

Authors: James Ho CS et al.

Journal: Future Medicine (2012)

Research Areas: Cancer research

Keywords: Review, clinical studies, conserved death, pathways, HAMLET, cancer therapies, protein folding, protein–lipid complex, tumor cell death, tumor, specificity, Action of HAMLET

Dermatan Sulfate Is Involved in the Tumorigenic Properties of Esophagus Squamos Cell Carcinom

Authors: Martin A. Thelin et al.

Journal: Cancer Research (2012)

Research Areas: Cancer research

Cell Lines: TE1

Keywords: HoloMonitor, Cell morphology

HAMLET Binding to Α-actinin Facilitates Tumor Cell Detachment

Authors: Maria Trulsson et al.

Journal: PLOS ONE (2011)

Research Areas: Cancer research

Cell Lines: A549

Keywords: HoloMonitor M2, Cell morphology, carcinoma, Integrins, Cell death, Small interfering RNA, Transfection, Cell staining, Cytoskeleton, Co-immunoprecipitation, Action of HAMLET

Digital Holography and Cell Studies

Authors: Kersti Alm et al.

Journal: Holography-Research and technologies (2011)

Research Areas: Method development

Keywords: Digital holographic technology

Generation of Trisomies in Cancer Cells by Multipolar Mitosis and Incomplete Cytokinesis

Authors: David Gisselsson david.gisselsson_nord@med.lu.se et al.

Journal: PNAS (2010)

Research Areas: Cancer research

Cell Lines: WiT-49

Keywords: HoloMonitor M2, cell division, nondisjunction, aneuploidy, centrosome

Reduction of the Putative CD44+CD24 Breast Cancer Stem Cell Population by Targeting the Polyamine Metabolic Pathway With Pg11047

Authors: Helenaa Cirenajwis et al.

Journal: Anticancer Drugs (2010)

Research Areas: Drug research

Cell Lines: JIMT-1

Keywords: HoloMonitor M2, cell motility, breast cancer stem cells, mesenchymal-to-epithelial transition, [1N, 12N]bis(ethyl)-cis-6, 7-dehydrospermine, polyamine analogue, drug development

Immunomodulatory Nanoparticles as Adjuvants and Allergen-delivery System to Human Dendritic Cells: Implications for Specific Immunotherapy

Authors: Sissela Broos et al.

Journal: Vaccine (2010)

Research Areas: Immunology

Cell Lines: MoDC

Keywords: HoloMonitor M2, Cell morphology, Allergy, Antigen presentation, Vaccination, Immunotherapy

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