Peer-reviewed Publications

Below you will find summaries and links to peer-reviewed publications and book chapters discussing HoloMonitor, its applications and the core technology — digital holographic and quantitative phase imaging (QPI) microscopy.

Enter cell line, author or any other phrase or word you would like to search for and click .

A new understanding of Acanthamoeba castellanii: dispelling the role of bacterial pore-forming toxins in cyst formation and amoebicidal actions

Authors: Yabrag et al.

Journal: Cell Death Discovery (2025)

Research Areas: Environmental Microbiology

Cell Lines: A, castellanii (bacteria), RAW 264, 7 macrophage

Keywords: HoloMonitor M4, cell morphology, bacterial infection, environmental microbiology

Novel Low-Cytotoxic and Highly Efficient Type I Photoinitiators for Visible LED-/Sunlight-Induced Photopolymerization and High-Precision 3D Printing

Authors: Liu et al.

Journal: Angewandte Chemie International Edition (2025)

Research Areas: Molecular chemistry

Cell Lines: C3H10 T1/2

Keywords: HoloMonitor M4, Kinetic dose response, kinetic motility assay, morphology, Single cell tracking

HYDRA: HYdrogel Dispensing with Robotic Automation for high throughput drug testing [not peer-reviewed]

Authors: Eloisa Torchia et al.

Journal: bioRxiv (2024)

Research Areas: Cell Culture

Cell Lines: HaCaT

Keywords: fish gelatin, HaCaT keratinocytes, phase holographic imaging, nocodazole, paclitaxel

Cells Prioritize the Regulation of Cell Mass Density [not peer-reviewed]

Authors: Jinyu Fu et al.

Journal: bioRxiv (2024)

Research Areas: Cell Biology

Cell Lines: NIH3T3, HT1080, T47D, Hs578, RPE 2n, RPE 4n, MCF-10A, MDA-MB-231, and its single cell clones (SCCs) MDA-SCC-1006, MDA-SCC-1304, and MDA-SCC-1308

Keywords: cell mass density, macromolecular crowding, cell regulation, osmolarity, environmental stress, fluorescence eXclusion method, quantitative phase microscopy

Lactobacilli-host interactions inhibit Staphylococcus aureus and Escherichia coli-induced cell death and invasion in a cellular model of infection

Authors: Despoina Eugenia Kiousi et al.

Journal: Frontiers in Microbiology (2024)

Research Areas: Infection Response

Cell Lines: HT-29

Keywords: probiotics, proteomics, transcriptomics, lactiplantibacillus plantarum, pathogen-induced cytotoxicity, pathogen invasion, competitive exclusion, dual rna-seq

High-Performance Sunlight-Induced Polymerized Hydrogels and Applications in 3D and 4D Printing

Authors: Ji Feng et al.

Journal: Small (2024)

Research Areas: Material Chemistry

Cell Lines: C3H10 T1/2

Keywords: 3D printing, 4D printing, sunlight polymerized hydrogels, sunlight‐induced photopolymerization, water‐soluble photoinitiator

Nuclear Overexpression of SAMHD1 Induces M Phase Stalling in Hepatoma Cells and Suppresses HCC Progression by Interacting with the Cohesin Complex

Authors: Juntang Shao et al.

Journal: Advanced Science (2024)

Research Areas: Cancer Research

Cell Lines: HEK293T cells (GNHu44), HepG2 cells (TCHu72) and Huh7 cells (TCHu182)

Keywords: HoloMonitor M4, Kinetic cell proliferation, Kinetic cell motility, cell cycle, cohesin complex, HCC, SAMHD1

The Yin and Yang of hsa-miR-1244 expression levels during activation of the UPR control cell fate

Authors: Paulina Czechowicz et al.

Journal: Cell Communication and Signaling (2024)

Research Areas: Apoptosis Regulation

Cell Lines: HeLa S3, Calu3, 16HBE14o-

Keywords: cell biology, protein-ligand interactions, receptors, cytokines and growth factors

Real-time morphometric analysis of targeted therapy for neuroblastoma cells in monolayer and 3D hydrogels using digital holographic microscopy

Authors: Sofia Granados-Aparici et al.

Journal: iScience (2024)

Research Areas: Cancer Research

Cell Lines: SK-N-BE (2), SH-SY5Y

Keywords: cancer, cell biology, mechanobiology, methodology in biological sciences

FOXO3A Plays a Role in Wound Healing by Regulating Fibroblast Mitochondrial Dynamics

Authors: Mariko Moriyama et al.

Journal: Journal of Investigative Dermatology (2024)

Research Areas: Woundhealing

Cell Lines: Primary fibroblasts

Keywords: fibroblasts, FOXO, migration, mitochondria, wound healing

Methods to Investigate Cell Migration

Authors: Anke Brüning-Richardson et al.

Journal: Cell Migration in Development, Health and Disease (2024)

Research Areas: Cell Biology

Keywords: cell motility cancer invasion, metastasis, cell development, cell migration in 3D environment, modelling cell migration in 3D, mathematical modelling of cell migration, analysis of cell migration, imaging of cell migration

Morphological and Optical Profiling of Melanocytes and SK-MEL-28 Melanoma Cells Via Digital Holographic Microscopy and Quantitative Phase Imaging

Authors: Ayah A Farhat et al.

Journal: Advanced Biology (2024)

Research Areas: Cancer research

Cell Lines: melanocytes and SK-MEL-28 melanoma cells

Keywords: HoloMonitor M4, Cell Migration, Cell Morphology, Digital Holographic Microscopy, Melanocytes, Melanoma, Quantitative Phase Imaging (QPI), SK‐MEL‐28 Cells

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Featured Publications

Cytocentric measurement for regenerative medicine

Authors: Henn et al.

Journal: Frontiers in Medical Technology (2023)

Research Areas: Regenerate Medicine

Keywords: Digital holographic imaging, regenerative medicine, tissue engineering, cell culture techniques, organoids, stem cells

Exploiting the potential of commercial digital holographic microscopy by combining it with 3D matrix cell culture assays

Authors: Monica Hellesvik et al.

Journal: Scientific Reports (2020)

Research Areas: Method Development

Cell Lines: NCL-H524, U2OS

Keywords: HoloMonitor M4, Cell movements, Cell morphology, Wound Healing, Cell Invasion

Digital Holographic Imaging as a Method for Quantitative, Live Cell Imaging of Drug Response to Novel Targeted Cancer Therapies

Authors: Laura V. Croft et al.

Journal: Theranostics: Methods and Protocols (2019)

Research Areas: Cancer research

Cell Lines: HeLa

Keywords: HoloMonitor M4, cell proliferation, cell morphology